Research Journal of Pharmacy and Technology

Taras V. Upyr ¹, Larysa V. Lenchyk ¹, Mykola А. Komisarenko ¹, Andriy M. Komisarenko , Ganjina F. Navruzzoda ², Tetiana P. Osolodchenko ³, Svitlana V. Ponomarenko ³

Affiliations
1 National University of Pharmacy, Kharkiv,, UA
2 Tajik National University Dushanbe,, TJ
3 Ilya Mechnikov Institute of Microbiology and Immunology, Kharkiv,, UA

Abstract

Prunus domestica - is one of the main fruit crops in Ukraine with a production of about 200 tons per year. In the world over then 2000 varieties of this plant are grown. In Ukraine, the following varieties of plums are zoned: Anna Shpet, Renklod Altana, Ugorka Stanley, Ugorka Italian, Ugorka Azhanska, and others. This plant is the valuable source of polysaccharides and phenolic compounds. That is why plum fruits are a part of many dietary supplements with laxative and anti-inflammatory activity in treating chronic constipation. In our previous research, we studied the chemical composition of alcohol extracts and polysaccharide complex of plum fruits. Following types of pharmacological activities: diuretic, membrane stabilizing, anticoagulant laxative, hepatoprotective, were confirmed in the analysed substances. In the article, we present the results of a study of the chemical composition of the plum presscake that remained after the plum juice was obtained. The composition of phenolic compounds was analyzed by using TLC, SF and HPLC methods. Antimicrobial activity of the alcohol extract of plum presscake was investigated by agar diffusion method. The results obtained indicate the possibility of complex processing of raw materials and obtaining new antimicrobial drugs from the presscake of plum juice production.

Keywords

Prunus domestica, fruits, presscake, phenolic compounds, antimicrobial activity.

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